Maurizio Mochetti was born in 1940 in Rome, where he currently lives and works.
In 1968 he made his debut on the Roman art scene with his first solo exhibition, Dieci progetti di Maurizio Mochetti, at the ‘La Salita’ Gallery. In 1969 he won the first edition of the ‘Premio Pascali’ in Polignano a Mare and, in the same year, the ‘Premio Scultura’ at the 6th Biennale Giovani in Paris.

In 1970 he participated in his first Venice Biennale, followed by those of 1978, 1982, 1986, 1988 and 1997. 
Since the early 1970s he has appeared on the international scene, participating in the 1976 Biennale Sydney Biennial in 1976, the Nagoya International Biennial in 1991 and the 24th São Paulo Biennial in 1998.
In 1988 he was invited as artist-in-residence at the Exploratorium in San Francisco (USA).